
Piprized TZ 4.5 gm Injection
Piprized TZ 4.5 gm Injection is a combination of Piperacillin and Tazobactam used to treat severe bacterial infections in hospital settings.
Piprized TZ 4.5 gm Injection by ZOTA is a powerful intravenous antibiotic containing Piperacillin (4 gm) and Tazobactam (0.5 gm). This combination belongs to the penicillin class of antibiotics and is highly effective against a wide range of Gram-positive and Gram-negative bacteria, including beta-lactamase-producing strains. It is primarily used in hospital or clinical settings for managing moderate to severe infections like pneumonia, intra-abdominal infections, urinary tract infections, and septicemia. Tazobactam acts as a beta-lactamase inhibitor, enhancing the efficacy of Piperacillin.
✅ Uses
Hospital-acquired and community-acquired pneumonia
Severe urinary tract infections (UTIs)
Intra-abdominal infections (e.g., peritonitis)
Septicemia and bacteremia
Skin and soft tissue infections
Gynecological infections
Bone and joint infections
🌿 Benefits
Broad-spectrum coverage including resistant bacteria
Effective in treating life-threatening infections
Inhibits beta-lactamase enzymes for better antibiotic action
Trusted in critical care and emergency medicine
Convenient once/twice-daily dosing under supervision
⚠️ Side Effects
Diarrhea or nausea
Rash or allergic reaction
Injection site inflammation
Elevated liver enzymes
Electrolyte imbalances (e.g., low potassium)
Rarely, seizures (at high doses in renal impairment)
💊 How to Use
Administered intravenously under medical supervision
Dosage and frequency based on severity and kidney function
Ensure proper dilution and infusion over 20–30 minutes
Do not self-administer
🛡️ Safety Advice
Use only in a hospital or clinic under doctor’s supervision
Inform your doctor if allergic to penicillins or cephalosporins
Monitor kidney and liver function regularly during use
Dose adjustment required in renal impairment
Not recommended in pregnancy/lactation unless necessary