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About Phenylephrine+paracetamol+cetirizine

Phenylephrine+paracetamol+cetirizine belongs to a category of  'cough and cold medications' primarily used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a sick person sneezes, coughs or talks.

Phenylephrine+paracetamol+cetirizine contains Cetirizine (antihistamine/antiallergic), Phenylephrine (decongestant) and Paracetamol (mild analgesic and antipyretic). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Phenylephrine+paracetamol+cetirizine should be taken as prescribed by the doctor. Your doctor will recommend how often you take Phenylephrine+paracetamol+cetirizine based on your medical condition. Some people may experience drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Everyone doesn't need to experience the above side effects. Most of these side effects of Phenylephrine+paracetamol+cetirizine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting Phenylephrine+paracetamol+cetirizine. If you have high blood pressure (hypertension),  liver or kidney disease, or coronary artery disease (heart disease), avoid using Phenylephrine+paracetamol+cetirizine as it may worsen your condition. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Phenylephrine+paracetamol+cetirizine if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline and Tranylcypromine) in the last 14 days. Intake of more than 4 gm of paracetamol can damage your liver, so it is better to avoid the use of Phenylephrine+paracetamol+cetirizine in severe liver damage. Cetirizine present in the Phenylephrine+paracetamol+cetirizine can make you sleepy, so do not drive or operate heavy machinery after taking Phenylephrine+paracetamol+cetirizine. Phenylephrine in Phenylephrine+paracetamol+cetirizine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers).

Uses of Phenylephrine+paracetamol+cetirizine

Treatment of Common cold, Allergies (allergic rhinitis).

Medicinal Benefits

Phenylephrine+paracetamol+cetirizine is primarily used to treat the common cold and allergy symptoms such as runny nose, blocked nose, sneezing, congestion, pain & fever. It is composed of three medicines, namely, Cetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (mild analgesic and antipyretic). Cetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Phenylephrine+paracetamol+cetirizine

  • Drowsiness
  • Nausea
  • Fatigue
  • Dryness in the mouth
  • Headache
  • Vomiting

Drug Warnings

Do not take Phenylephrine+paracetamol+cetirizine if you are allergic to Phenylephrine+paracetamol+cetirizine, anti-histamine (cetirizine), analgesics (paracetamol), a decongestant (phenylephrine), or any of its ingredients. Please inform your doctor if you are pregnant or breastfeeding before starting Phenylephrine+paracetamol+cetirizine. If you have high blood pressure,  kidney or liver disease, or coronary artery disease, please do not take Phenylephrine+paracetamol+cetirizine as it is known to interact. Also, inform your doctor about all other medications you have taken before starting Phenylephrine+paracetamol+cetirizine. Do not stop taking Phenylephrine+paracetamol+cetirizine even if you feel better without asking your doctor, as your symptoms may come back and even worsen your condition. Phenylephrine+paracetamol+cetirizine may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Phenylephrine+paracetamol+cetirizine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days. Also, avoid tobacco consumption as it may worsen your condition further.

Drug Interactions

Drug-Drug Interactions: Phenylephrine+paracetamol+cetirizine may interact with blood thinners (warfarin, aspirin), antibiotics (chloramphenicol), high cholesterol-lowering medicines (cholestyramine), anti-sickness drugs (domperidone, metoclopramide), anti-allergic drugs (diphenhydramine), drugs used to reduce acid in the stomach (pantoprazole), anti-depressants (isocarboxazid, rasagiline, linezolid, tranylcypromine).

Drug-Food Interactions: Avoid alcohol intake and tobacco consumption with Phenylephrine+paracetamol+cetirizine as it may cause increased drowsiness, dizziness, and lack of concentration.

Drug-Disease Interactions: If you have high blood pressure, kidney or liver problems, coronary artery disease, or are receiving monoamine oxidase inhibitor (MAO) therapy, inform your doctor before taking Phenylephrine+paracetamol+cetirizine.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • ASPIRIN
  • CHLORAMPHENICOL
  • CHOLESTYRAMINE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • PANTOPRAZOLE
  • ISOCARBOXAZID
  • RASAGILINE
  • LINEZOLID
  • TRANYLCYPROMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Phenylephrine+paracetamol+cetirizine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Phenylephrine+paracetamol+cetirizine.

    • Safety Warning

      Pregnancy

      caution

      The safety of Phenylephrine+paracetamol+cetirizine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      The safety of Phenylephrine+paracetamol+cetirizine in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

    • Safety Warning

      Driving

      unsafe

      Phenylephrine+paracetamol+cetirizine may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Phenylephrine+paracetamol+cetirizine.

    • Safety Warning

      Liver

      caution

      Take Phenylephrine+paracetamol+cetirizine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Phenylephrine+paracetamol+cetirizine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Phenylephrine+paracetamol+cetirizine is not recommended for children below 12 years of age. However, please consult a doctor before giving Phenylephrine+paracetamol+cetirizine to children

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